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| Home < Centre de recherche < Publications 2010 < Publications 2008 |     |
| Info.onco@chuv.ch |
2008 |
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| 1: | Alghisi G.-C., L. Ponsonnet, and C. Rüegg. | |
| The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells
PLoS ONE, 4(2): e4449 |
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| 2: | Azria D, Ozsahin M, Gligorov J, Zaman K, Llacer Moscardo C, Lemanski C, Jacot W, Belkacémi Y. | |
| [How to combine hormonotherapy and radiation treatment in adjuvant breast cancer?]
Cancer Radiother. 2008 Jan;12(1):37-41 |
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| 3: | Baruthio F, Quadroni M, Rüegg C, Mariotti A. | |
| Proteomic analysis of membrane rafts of melanoma cells identifies protein patterns characteristic of the tumor progression stage.
Proteomics. 2008 Nov;8(22):4733-47. |
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| 4: | Baumert BG., Stupp R. | |
| European Organization for Research and Treatment of Cancer (EORTC) Radiation Oncology Group; European Organization for Research and Treatment of Cancer (EORTC) Brain Tumor GroupLow-grade glioma: a challenge in therapeutic options: the role of radiotherapy
Ann Oncol. 2008 Sep;19 Suppl 7:vii217-22. |
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| 5: | Brandes AA., Franceschi E., Tosoni A., Hegi ME., Stupp R. | |
| Epidermal growth factor receptor inhibitors in neuro-oncology: hopes and disappointments.
Clin Cancer Res. 2008 Feb 15;14(4):957-60. |
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| 6: | Brembilla N.C., I. Cohen-Salmon, J.Weber, C. Rüegg, M. Quadroni, K. Harshman and M. A. Doucey (2008). | |
| Profiling of signaling proteins and T cell receptor signaling complex assembly in human CD4 T lymphocytes using RP protein arrays
Proteomics. 2009 Jan;9(2):299-309. |
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| 7: | Brembilla NC, Weber J, Rimoldi D, Pradervand S, Schütz F, Pantaleo G, Rüegg C, Quadroni M, Harshman K, Doucey MA | |
| c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells.
Blood. 2008 Aug 1;112(3):652-60. Epub 2008 May 27. |
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| 8: | Buchegger F, PRESS OW, Bischof Delaloye A, Ketterer N. | |
| Radiolabeled and native antibodies and the prospect of cure of follicular lymphoma
Oncologist. 2008 Jun;13(6):657-67 |
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| 9: | Capendeguy, O., Iwaszkiewicz, J., Michielin, O. & Horisberger, J. D. | |
| The fourth extracellular loop of the alpha subunit of Na,K-ATPase. Functional evidence for close proximity with the second extracellular loop
J Biol Chem. 2008 Oct 10;283(41):27850-8. Epub 2008 Aug 8. |
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| 10: | Cherix S., Speiser M., Matter M., Raffoul W., Liénard D., Theumann N., Mouhsine E., Mirimanoff R.O., Leyvraz S., Lejeune F.J., Leyvraz P.F. | |
| Isolated limb perfusion with tumor necrosis factor and Melphalan for non-resectable soft tissue sarcomas : long-term results on efficacy and limb salvage in a selected group of patients.
Journal of Surgical Oncology 98 : 148-155, 2008. |
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| 11: | Chodanowski, P., Grosdidier, A., Feytmans, E. & Michielin, O. | |
| Local alignment refinement using structural assessment
PLoS ONE. 2008 Jul 9;3(7):e2645. |
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| 12: | Cuendet, M. A. & Michielin, O. | |
| Protein-Protein Interaction Investigated by Steered Molecular Dynamics: the TCR-pMHC Complex
Biophys J 95, 3575-3590 (2008). |
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| 13: | D'Addario G., Rauch D., Stupp R., Pless M., Stahel R., Mach N., Jost L., Widmer L., Tapia C., Bihl M., Mayer M., Ribi K., Lerch S., Bubendorf L., Betticher DC | |
| Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03.
Ann Oncol. 2008 Apr;19(4):739-45. Epub 2007 Dec 19. |
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| 14: | Degen M, Brellier F, Schenk S, Driscoll R, Zaman K, Stupp R, Tornillo L, Terracciano L, Chiquet-Ehrismann R, Rüegg C, Seelentag W. | |
| Tenascin-W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients.
Int J Cancer. 2008 Jun 1;122(11):2454-61. |
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| 15: | Derre, L., Bruyninx, M., Baumgaertner, P., Ferber, M., Schmid, D., Leimgruber, A., Zoete, V.,Romero, P., Michielin, O., Speiser, D. E. & Rufer, N. | |
| Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues.
Proc Natl Acad Sci U S A 105, 15010-15015 (2008). |
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| 16: | Eisen T., Thatcher N., Leyvraz S., Miller W.H., Couture F., Lorigan P., Luthi F., Small D., Tanovic A., O’Brien M. | |
| Phase II study of weekly plitidepsin as second-line therapy for small cell lung cancer.
Lung Cancer Aug 7, 2008, |
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| 17: | Frossard V, Ketterer N, Rosselet A, Meier P, Cairoli A, Duchosal MA, Kovacsovics T. | |
| Early intensification and autologous stem cell transplantation in patients with systemic AL amyloidosis: a single-centre experience.
Annals of Hematology 2008 Dec 6. |
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| 18: | Gay B. , Taylor KI, Hohl U, Tolnay M, Staehelin HB | |
| The validity of clinical diagnoses of dementia in a group of consecutively autopsied memory clinic patients.
J Nutr Health Aging. 2008 Feb;12(2):132-7. |
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| 19: | Gorlia T., Van den Bent MJ., Hegi ME., Mirimanoff RO., Weller M., Cairncross JG., Eisenhauer E., Belanger K., Brandes AA., Allgeier A., Lacombe D., Stupp R. | |
| Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3.
Lancet Oncol. 2008 Jan;9(1):29-38. Epub 2007 Dec 21 |
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| 20: | Grosdidier, A., Zoete, V. & Michielin, O. | |
| Blind docking of 260 protein-ligand comlexes using EADock 2.0.
J. Comput. Chem. In print (2008). |
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| 21: | Gruber G, Cole BF, Castiglione-Gertsch M, Holmberg SB, Lindtner J, Golouh R, Collins J, Crivellari D, Thürlimann B, Simoncini E, Fey MF, Gelber RD, Coates AS, Price KN, Goldhirsch A, Viale G, Gusterson BA, International Breast Cancer Study Group | |
| International Breast Cancer Study Group. Extracapsular tumor spread and the risk of local, axillary and supraclavicular recurrence in node-positive, premenopausal patients with breast cancer.
Ann Oncol. 2008 Aug;19(8):1393-401. Epub 2008 Apr 2. |
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| 22: | Hegi ME., Liu L., Herman JG., Stupp R., Wick W., Weller M., Mehta MP., Gilbert M-R. | |
| Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity.
J Clin Oncol. 2008 Sep 1;26(25):4189-99. Review |
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| 23: | Hildebrand J., Gorlia T., Kros JM., Afra D., Frenay M., Omuro A., Stupp R., Lacombe D., Allgeier A., Van den Bent MJ. | |
| EORTC Brain Tumour Group investigators Related Articles Free article at journal site Adjuvant dibromodulcitol and BCNU chemotherapy in anaplastic astrocytoma: results of a randomised European Organisation for Research and Treatment of Cancer phase III study (EORTC study 26882).
Eur J Cancer. 2008 Jun;44(9):1210-6. Epub 2008 Jan 14 |
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| 24: | Hottinger A-F., Stupp R. | |
| Therapeutic strategies for the management of gliomas
Rev Neurol (Paris). 2008 Jun-Jul;164(6-7):523-30. Epub 2008 May 13. Review |
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| 25: | Iancu EM, Speiser DE, Rufer N. | |
| Assessing ageing of individual T lymphocytes: mission impossible?
Mech Ageing Dev. 2008 129(1-2):67-78. |
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| 26: | Italiano A., Penel N., Robin Y.M., Bui B., Le Cesne A., Piperno-Neumann S., Tubiana-Hulin M., Bompas E., Chevreau C., Cupissol D., Domont J., Duffaud F., Isambert N., Leroux A., Leyvraz S., Pabot du Chatelard P., Thyss A., Coindre J.M., Blay J.Y. | |
| Neo/adjuvant chemotherapy does not improve outcome in resected primary synovial sarcoma : a study of the French Sarcoma Group
Ann. Oncol. 19 : 2111-2123, 2008. |
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| 27: | Kiefer T, Krüger WH, Montemurro M, Schüler F, Hirt C, Pasold R, Niederwieser DSchwenke M, Dölken G | |
| Mobilization of hemopoietic stem cells with high-dose methotrexate plus granulocyte-colony-stimulating factor in patients with primary central nervous system lymphoma.Transfusion.
Transfusion. 2008 Dec;48(12):2624-8. Epub 2008 Sep 17. |
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| 28: | Kirjavainen, A., Sulg, M., Heyd, F., Alitalo, K., Ylä-Herttuala, S., Möröy, T., Petrova, T.V., Pirvola, U. | |
| Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia
Dev Biol. 2008 Oct 1;322(1):33-45. Epub 2008 Jul 9 |
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| 29: | Lamers L-M., Stupp R., Van den Bent M.J, Al M-J., Gorlia T., Wasserfallen J-B., Mittmann N., Jin Seung S., Crott R., Uyl-de Groot C-A. | |
| EORTC 26981/22981 NCI-C CE3 Intergroup Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study.
Cancer. 2008 Mar 15;112(6):1337-44. |
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| 30: | Leyvraz S, Pampallona S, Martinelli G, Ploner F, Perey L, Aversa S, Peters S, Brunsvig P, Montes A, Lange A, Yilmaz U, Rosti G; Solid Tumors Working Party of the European Group for Blood and Marrow Transplantation, 2008 | |
| A threefold dose intensity treatment with ifosfamide, carboplatin, and etoposide for patients with small cell lung cancer: a randomized trial
J Natl Cancer Inst. 2008 Apr 16;100(8):533-41. Epub 2008 Apr 8 |
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| 31: | Lorusso G, Rüegg C. | |
| The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol.
Histochem Cell Biol. 2008 Dec;130(6):1091-103. Epub 2008 Nov 6 |
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| 32: | Maby-El Hajjami H, & Petrova T.V. (2008) | |
| Developmental and pathological lymphangiogenesis: from models to human disease
Histochem Cell Biol. 2008 Dec;130(6):1063-78. Epub 2008 Oct 23. Review |
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| 33: | Michielin, O., Rufer, N., Romero, P., Laurent, J., Cerottini, J. P., Gugisberg, D., Leyvraz, S. & Speiser, D. | |
| New developments in cancer immunotherapy
Rev Med Suisse. 2008 May 21;4(158):1248-51. Review. French. |
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| 34: | Monnier Y., P. Farmer, G. Bieler, N. Imaizumi, T. Sengstag, G.C. Alghisl, J.C. Stehle, L. Ciarloni, S. Andrejevic-Blant, R. Moeckli, R.O. Mirimanoff, SL. Goodman, M. Delorenzi, C. Rüegg (2008). | |
| CYR61 and aVb5 integrin cooperate to promote invasion and metastasis of tumors growing in pre-irradiated stroma
Cancer Res. 2008 Sep 15;68(18):7323-31. |
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| 35: | Montemurro M, Achtari L, Röth A, Halkic N, Luthi F, Ozsahin M, Denys A, Bauer J, Demartines N, Leyvraz S. | |
| Systemic treatment of metastatic colorectal
Rev Med Suisse. 2008 May 21;4(158):1254-7. Links |
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| 36: | Murat A., Migliavacca E., Gorlia T., Lambiv WL., Shay T., Hamou MF., de Tribolet N., Regli L., Wick W., Kouwenhoven MC., Hainfellner JA., Heppner FL., Dietrich PY., Zimmer Y., Cairncross JG., Janzer RC., Domany E., Delorenzi M., Stupp R., Hegi ME. | |
| Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.
J Clin Oncol. 2008 Jun 20;26(18):3015-24 |
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| 37: | Neyns B., Hoorens A., Stupp R. | |
| Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
Acta Neurol Belg. 2008 Dec;108(4):131-4. |
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| 38: | Petrova, T.V.*, Nykänen, A., Norrmén,C., Ivanov, K.I., Andersson, L.C., Haglund, C., Puolakkainen, P.,Wempe, F., von Melchner, H., Gradwohl, G., Vanharanta, S., Aaltonen, L.A., Saharinen, J., Gentile, M., Clarke, A., Taipale, J., Oliver, G., & Alitalo, K.* (2008) | |
| Homeobox transcription factor PROX1 induces progression of colon cancer by promoting the transition from benign to highly dysplastic phenotype,
Cancer Cell. 2008 May;13(5):407-19. |
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| 39: | Petrova, T.V., Bono, P., Holnthoner,W., Chesnes, J.,Pytowski, B., Sihto, H., Laakkonen, P., Heikkilä, P., Joensuu, H.,&Alitalo, K. (2008) | |
| VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors
Cancer Cell. 2008 Jun;13(6):554-6. |
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| 40: | Preusser M., Charles Janzer R., Felsberg J., Reifenberger G., Hamou MF., Diserens AC., Stupp R., Gorlia T., Marosi C., Heinzl H., Hainfellner JA., Hegi M. | |
| Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.
Brain Pathol. 2008 Oct;18(4):520-32. Epub 2008 Apr 8 |
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| 41: | Prior J., Montemurro M., Orcurto M-V., Michielin O., Luthi F, Benhattar J., Guillou L., Elsig V., Stupp R., Bischof Delaloye A, Leyvraz S. | |
| Early Prediction of Response to Sunitinib After Imatinib Failure by 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients With Gastrointestinal Stromal Tumor.
J Clin Oncol. 2009 Jan 20;27(3):439-45. Epub 2008 Dec 8. |
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| 42: | Rüegg C., J.D. Tissot, P. Farmer and A. Mariotti (2008). | |
| The omics revolution meets hypothesis-driven research: partnership for innovative discoveries in vascular biology and angiogenesis.
Thromb Haemost. 2008 Nov;100(5):738-46. |
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| 43: | Raymond E., Brandes A-A., Dittrich C., Fumoleau P., Coudert B., Clement P-M., Frenay M., Rampling R., Stupp R., Kros J-M., Heinrich M-C., Gorlia T., Lacombe D., van den Bent M-J. | |
| European Organisation for Research and Treatment of Cancer Brain Tumor Group Study. Phase II study of imatinib in patients with recurrent gliomas of various histologies: a European Organisation for Research and Treatment of Cancer Brain Tumor Group Study.
J Clin Oncol. 2008 Oct 1;26(28):4659-65 |
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| 44: | Reardon D-A., Nabors L-B., Stupp R., Mikkelsen T. | |
| Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma Expert Opin Investig Drugs.
2008 Aug;17(8):1225-35. Review. |
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| 45: | Rebeaud F, Hailfinger S, Posevitz-Fejfar A, Tapernoux M, Moser R, Rueda D, Gaide O, Guzzardi M, Iancu EM, Rufer N, Fasel N, Thome M. | |
| The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
Nat Immunol. 2008 Mar;9(3):272-81. Epub 2008 Feb 10. |
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| 46: | Regan MM, Pagani O, Walley B, Torrisi R, Perez EA, Francis P, Fleming GF, Price KN, Thürlimann B, Maibach R, Castiglione-Gertsch M, Coates AS, Goldhirsch A, Gelber RD; SOFT/TEXT/PERCHE Steering Committee; International Breast Cancer Study Group. | |
| Premenopausal endocrine-responsive early breast cancer: who receives chemotherapy?
Ann Oncol. 2008 Jul;19(7):1231-41. Epub 2008 Mar 5. |
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| 47: | Ribi K., Bernhard J., Schuller J-C., Weder W., Bodis S., Jörger M., Betticher D., Schmid R-A., Stupp R., Ris H-B., Stahel R-A. ; Swiss Group for Clinical Cancer Research SAKK. | |
| Individual versus standard quality of life assessment in a phase II clinical trial in mesothelioma patients: feasibility and responsiveness to clinical changes.
Lung Cancer. 2008 Sep;61(3):398-404. Epub 2008 Apr 22 |
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| 48: | Rochat, B., Zoete, V., Grosdidier, A., von Grunigen, S., Marull, M. & Michielin, O. | |
| In vitro biotransformation of imatinib by the tumor expressed CYP1A1 and CYP1B1
Biopharm Drug Dispos. 2008 Mar;29(2):103-18. |
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| 49: | Rohrig, U. F., Grosdidier, A., Zoete, V. & Michielin, O. | |
| Docking to heme proteins
J Comput Chem. 2009 Mar 13. |
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| 50: | Ronet C., Voigt H., Himmelrich H., Doucey M.-A., Breton M., Hauyon-Latorre Y., Tacchini-Cottier F., Bron C., Louis J. and Launois P. L. | |
| Major-specific B cells are necessary for Th2 cell development and susceptibility to infection with L. Major LV39
J Immunol. 2008 Apr 1;180(7):4825-35. |
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| 51: | Rossier-Pansier L., F. Baruthio, C. Rüegg, A. Mariotti (2008). | |
| Compartmentalization in membrane rafts defines a pool of N-cadherin associated with catenins and not engaged in cell-cell junctions in melanoma cells.
J Cell Biochem. 2008 Feb 15;103(3):957-71. |
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| 52: | Sessa C, Guibal A, Del Conte G, Rüegg C, Medscape | |
| Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations ?
Nat Clin Pract Oncol. 2008 Jul;5(7):378-91. Epub 2008 Jun 17. |
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| 53: | Speiser DE, Baumgaertner P, Voelter V, Devevre E, Barbey C, Rufer N, Romero P. | |
| Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3849-54. Epub 2008 Mar 4. |
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| 54: | Stiefel F, Krenz S, Zdrojewski C, Stagno D, Fernandez M, Bauer J, Fucina N, Luthi F, Leyvraz S, Borasio GD, Fegg M. | |
| Meaning in life assessed with the Schedule for Meaning in Life Evaluation(SMiLE): a comparison between a cancer patient and student sample
Support Care Cancer. 2008 Oct;16(10):1151-5. Epub 2008 Jan 16. |
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| 55: | Stupp R., Hottinger AF., Van den Bent M-J., Dietrich P-Y., Brandes A-A. | |
| Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers.
Ann Oncol. 2008 Sep;19 Suppl 7:vii209-16. |
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| 56: | Stupp R., Hottinger AF. | |
| Management of malignant glioma--quo vadis ?
Onkologie. 2008 Jun;31(6):300-2. Epub 2008 May 27. |
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| 57: | Stupp R., Roila F.; ESMO Guidelines Working Group | |
| Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up.
Ann Oncol. 2008 May;19 Suppl 2:ii83-5. |
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| 58: | Thadikkaran L, Rufer N, Benay C, Crettaz D, Tissot JD | |
| Methods for human CD8(+) T lymphocyte proteome analysis
Methods Mol Biol. 2008;484:45-65. |
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| 59: | Voelter V, Pica A, Laurent J, Rimoldi D, Bouzourene H, Sajadi A, Matter M, Romero P, Rufer N, Speiser DE. | |
| An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain
Cancer Immun. 2008 Mar 27;8:6. |
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| 60: | Voelter V, Schalenbourg A, Pampallona S, Peters S, Halkic N, Denys A, Goitein G, Zografos L, Leyvraz S, 2008. | |
| Adjuvant intra-arterial hepatic fotemustine for high-risk uveal melanoma patients
Melanoma Res. 2008 Jun;18(3):220-4. |
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| 61: | Voelter V., Diserens AC, Moulin A, Nagel G, Yan P, Migliavacca E, Rimoldi D, Hamou MF, Kaina B, Leyvraz S, Hegi ME. | |
| Infrequent promoter méthylation of MGMT gene in liver metastases from uveal melanoma
Int J Cancer. 2008 Sep 1;123(5):1215-8. |
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| 62: | Voelter, V., Rufer, N., Reynard, S., Greub, G., Brookes, R., Guillaume, P., Grosjean, F., Fagerberg, T., Michielin, O., Rowland-Jones, S., Pinilla, C., Leyvraz, S., Romero, P. & Appay, V. | |
| Characterization of Melan-A reactive memory CD8+ T cells in a healthydonor
Int Immunol. 2008 Aug;20(8):1087-96. Epub 2008 Jun 23. |
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| 63: | Wagner D., Stahl M. | |
| Moeglichkeiten der systemischen Therapie im metastasierten Stadium
Der Onkologe 2008 · 14:381–388, Online publiziert: 9. März 2008 |
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| 64: | Wick W., Stupp R., Beule A-C., Bromberg J., Wick A., Ernemann U., Platten M., Marosi C., Mason W-P., van den Bent M., Weller M., Rorden C., Karnath H-O | |
| European Organisation for Research and Treatment of Cancer and the National Cancer Institute of Canada Clinical Trials Group. A novel tool to analyze MRI recurrence patterns in glioblastoma.
Neuro Oncol. 2008 Dec;10(6):1019-24. Epub 2008 Jul 31 |
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| 65: | Widmer N., L.A. Decosterd, S. Leyvraz, M.A. Duchosal, A. Rosselet, M. Debiec-Rychter, C. Csajka, J. Biollaz and T. Buclin | |
| Relationship of imatinib free plasma levels and target genotype with efficacy and tolerability
Br J Cancer. 2008 May 20;98(10):1633-40. Epub 2008 May 6. |
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| 66: | Yan H., Cheng C., Haouala A., Krueger T., Ballini J-P., Peters S., Decosterd LA, ILetovanec I, Ris H-B. and Andrejevic-Blant S., 2008 | |
| Distribution of Free and Liposomal Doxorubicin After Isolated Lung Perfusion in a Sarcoma Model
Ann Thorac Surg. 2008 Apr;85(4):1225-32. |
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| 67: | Zoete, V., Grosdidier, A. & Michielin, O. | |
| Docking, virtual high throughput screening and in silico fragment-based drug design
J Cell Mol Med. 2009 Feb;13(2):238-48. Epub 2009 Jan 21. |
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Dernière modification le
21.05.2010